Basic Information

Symbol
TRIM66
RNA class
mRNA
Alias
Tripartite Motif Containing 66 KIAA0298 C11orf29 TIF1D Tripartite Motif-Containing Protein 66 Transcriptional Intermediary Factor 1 Delta Chromosome 11 Open Reading Frame 29 Tripartite Motif-Containing 66 TIF1DELTA
Location (GRCh38)
11:8612037-8682694
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001388022.1
Sequence length
10695.0 nt
GC content
0.5058

Transcripts

ID Sequence Length GC content
NM_001388022.1 NCBI
GCUUCCUCUUUCUGAGGGUGGUGAUCCCCCAUCACGGAGUGUCCUGGUG… 10695 nt 0.5058
NM_001388023.1 NCBI
GCUUCCUCUUUCUGAGGGUGGUGAUCCCCCAUCACGGAGUGUCCUGGUG… 10584 nt 0.5055
NM_001388024.1 NCBI
AAGUUUCCGGGUCUUCCUCAGUCUGGAUGGCUGUGUGGAAAAAGCUUGG… 11047 nt 0.5092
NM_014818.2 NCBI
ACAGGAUAAGGACUUCAGGUGAAGUGGCAGGAGCAGGUGAGUAUGUAGG… 9800 nt 0.5063
Summary

Predicted to enable chromatin binding activity; identical protein binding activity; and zinc ion binding activity. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that the TRIM66 was the third most increased gene in female versus male E7.0 embryos, with a +4.8 Log2FC, and functions to push totipotent stem cells into a pluripotent state and deacetylates H3K56ac [Boschen et al. DOI:10.1002/Bdr2.2292].