Basic Information

Symbol
TRIM71
RNA class
mRNA
Alias
Tripartite Motif Containing 71 LIN41 LIN-41 Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase TRIM71 Tripartite Motif-Containing Protein 71 E3 Ubiquitin-Protein Ligase TRIM71 Protein Lin-41 Homolog Abnormal Cell LINeage LIN-41 Homolog Of C. Elegans Lin-41 EC 2.3.2.27 HYDCC1 HYC4
Location (GRCh38)
3:32817526-32897824
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001039111.3
Sequence length
8704.0 nt
GC content
0.4744

Transcripts

ID Sequence Length GC content
NM_001039111.3 NCBI
ACUCCCCCACCCACCUCGUCCGCUCUCUCCUCCUCCUCCUCCUCUUCCU… 8704 nt 0.4744
Summary

The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015]

Forensic Context

A study in *C. elegans* demonstrated that the TRIM71 functions as an RBCC protein that prevents expression of the LIN-29 transcription factor, and RNAi knockdown of the TRIM71 synergistically enhanced the precocious developmental phenotypes of *dre-1* mutants [Fielenbach et al. DOI:10.1016/j.devcel.2007.01.018].