Basic Information

Symbol
TRMT9B
RNA class
mRNA
Alias
TRNA Methyltransferase 9B (Putative) KIAA1456 TRM9L C8orf79 HTRM9L Probable TRNA Methyltransferase 9-Like Protein Probable TRNA Methyltransferase 9B FLJ36980 Chromosome 8 Open Reading Frame 79 EC 2.1.1.-
Location (GRCh38)
8:12945642-13031503
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020844.3
Sequence length
9591.0 nt
GC content
0.3922

Transcripts

ID Sequence Length GC content
NM_001099677.1 NCBI
GUCUUGGUUAGUUAAAAAAAAAAAAAAAGUUGGCCAGGCACAGUGGCUU… 9313 nt 0.3906
NM_020844.3 NCBI
AUUCAGUAUUGUGUAGUACAGAAAAGAUCACACAUGUAUAUGUCAGAAG… 9591 nt 0.3922
Summary

Enables tRNA methyltransferase activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A single-nucleus transcriptomics study in human postmortem brain tissue identified the TRMT9B as a protein coding gene downregulated in the MSN.3 cell type (a subset of medium spiny neurons) in individuals with alcohol use disorder compared to controls [Van Den Oord et al. DOI:10.1111/Adb.13250].