Basic Information

Symbol
TSHR
RNA class
mRNA
Alias
Thyroid Stimulating Hormone Receptor LGR3 Thyrotropin Receptor Thyroid-Stimulating Hormone Receptor Seven Transmembrane Helix Receptor Thyrotropin Receptor-I, HTSHR-I TSH Receptor HTSHR-I CHNG1 TSH-R
Location (GRCh38)
14:80954989-81146306
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_000369.5
Sequence length
4308.0 nt
GC content
0.4311

Transcripts

ID Sequence Length GC content
NM_000369.5 NCBI
GCAGAGCUGAGAAUGAGGCGAUUUCGGAGGAUGGAGAAAUAGCCCCGAG… 4308 nt 0.4311
NM_001018036.3 NCBI
GCAGAGCUGAGAAUGAGGCGAUUUCGGAGGAUGGAGAAAUAGCCCCGAG… 1081 nt 0.4514
NM_001142626.3 NCBI
GCAGAGCUGAGAAUGAGGCGAUUUCGGAGGAUGGAGAAAUAGCCCCGAG… 1144 nt 0.4528
Summary

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Forensic Context

No relevant information is available at the moment.