Basic Information

Symbol
TSPAN18
RNA class
mRNA
Alias
Tetraspanin 18 TSPAN Tetraspanin-18 Tspan-18
Location (GRCh38)
Forensic tag(s)
Sudden cardiac death diagnosis

MANE select

Transcript ID
NM_130783.5
Sequence length
4557.0 nt
GC content
0.5695

Transcripts

ID Sequence Length GC content
AGCUGCCGCCGGCGUCGCGGGGCUCCAGGCUGCGGGGCGGACGUAGCGC… 4557 nt 0.5695
Summary

Involved in regulation of sprouting angiogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that the TSPAN18 is a migrasome-related gene allocated to a kinetic pattern associated with lysosome and autophagy functions, showing decreasing expression along macrophage pseudo-time in cardiac Cd45+ cells from AMI-induced models [Zhu et al. DOI:10.3390/biomedicines12071626].