Basic Information

Symbol
TSPAN8
RNA class
mRNA
Alias
Tetraspanin 8 Transmembrane 4 Superfamily Member 3 CO-029 TM4SF3 Tumor-Associated Antigen CO-029 Tetraspanin-8 Tspan-8
Location (GRCh38)
12:71124454-71441898
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004616.3
Sequence length
1131.0 nt
GC content
0.3970

Transcripts

ID Sequence Length GC content
NM_001369760.1 NCBI
GCUUUCUCUUUCUGCUCUGAAGCCGUGGAUACAGAAAUCUCUGCAGGCA… 1083 nt 0.3952
NM_004616.3 NCBI
AGUGCCCCAGGAGCUAUGACAAGCAAAGGAACAUACUUGCCUGGAGAUA… 1131 nt 0.3970
Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.