Basic Information

Symbol
TUBA4B
RNA class
mRNA
Alias
Tubulin Alpha 4b TUBA4 Tubulin, Alpha 4b (Pseudogene) Tubulin-Like Protein Alpha-4B Tubulin, Alpha 4 FLJ13940 Putative Tubulin-Like Protein Alpha-4B Alpha-Tubulin 4B EC 3.6.5.-
Location (GRCh38)
2:219253243-219272197
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_001355221.1
Sequence length
1389.0 nt
GC content
0.5594

Transcripts

ID Sequence Length GC content
NM_001355221.1 NCBI
GUCUCUGCCCAUCCGCGCACCCGGGCUUCGGCUGGAGAGGGCCAGCUCG… 1389 nt 0.5594
Summary

Predicted to enable GTP binding activity; hydrolase activity; and metal ion binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cytoskeleton organization and microtubule-based process. Predicted to be located in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that in vivo α-particle irradiation of specific liver cell types (Kupffer or endothelial cells) induced distinct gene expression profiles, with the TUBA4B being down-regulated specifically following Kupffer cell-specific exposure [Roudkenar et al. DOI:10.1269/jrr.07078].