Basic Information

Symbol
TUBB2B
RNA class
mRNA
Alias
Tubulin Beta 2B Class IIb BA506K6.1 Class IIb Beta-Tubulin Tubulin Beta-2B Chain Tubulin, Beta 2B DKFZp566F223 MGC8685 Epididymis Secretory Sperm Binding Protein Tubulin, Beta Polypeptide Paralog Class II Beta-Tubulin Isotype CDCBM7 PMGYSA
Location (GRCh38)
6:3223324-3231730
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_178012.5
Sequence length
1922.0 nt
GC content
0.5614

Transcripts

ID Sequence Length GC content
NM_178012.5 NCBI
CUCAGCCCGUCGGUUCCCGAGCGCCUUCCCGGUGACCCCGCAGUGGGUG… 1922 nt 0.5614
Summary

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]

Forensic Context

A study in humans demonstrated that the TUBB2B was upregulated in the subcutaneous adipose tissue of heavier monozygotic co-twins compared to their leaner siblings, indicating its association with cellular protein metabolic processes in the context of obesity [Muniandy et al. DOI:10.1038/ijo.2017.95].