Basic Information
Symbol
UBAP1L
RNA class
mRNA
Alias
Ubiquitin Associated Protein 1 Like
Ubiquitin-Associated Protein 1-Like
UBAP-1L
Location (GRCh38)
15:65092760-65115200
Forensic tag(s)
Sudden cardiac death diagnosis
MANE select
Transcript ID
NM_001163692.2
Sequence length
1707.0 nt
GC content
0.6157
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| AUUCAUUUAUACACGCUUUGUCUGCAGGGAAGUUCUCCUGGUAAUUACA… | 1707 nt | 0.6157 |
Summary
Predicted to enable ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT I complex. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in human patients identified the UBAP1L as the most down-regulated mRNA in myocardial fibrosis after acute myocardial infarction [Wang et al. DOI:10.2147/IJGM.S329391], and a separate study found it was upregulated in heart failure compared to myocardial fibrosis [Wang et al. DOI:10.3389/fcvm.2021.664044].