Basic Information
Symbol
UBD
RNA class
mRNA
Alias
Ubiquitin Like Modifier D
Ubiquitin D
FAT10
HLA-F Adjacent Transcript 10
Ubiquitin-Like Protein FAT10
Diubiquitin
UBD-3
Location (GRCh38)
6:29555515-29559732
Forensic tag(s)
-
MANE select
Transcript ID
NM_006398.4
Sequence length
894.0 nt
GC content
0.4374
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| GUCUCUGGUUUCUGGCCCCUUGUCUGCAGAGAUGGCUCCCAAUGCUUCC… | 894 nt | 0.4374 |
Summary
This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types. [provided by RefSeq, Aug 2017]
Forensic Context
No relevant information is available at the moment.