Basic Information

Symbol
UGGT1
RNA class
mRNA
Alias
UDP-Glucose Glycoprotein Glucosyltransferase 1 HUGT1 UDP-Glucose Ceramide Glucosyltransferase-Like 1 UGCGL1 UDP-Glucose:Glycoprotein Glucosyltransferase 1 UDP--Glc:Glycoprotein Glucosyltransferase UGT1 EC 2.4.1.- EC 2.4.1 UGGT UGTR GT
Location (GRCh38)
2:128091151-128195677
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020120.4
Sequence length
10761.0 nt
GC content
0.4498

Transcripts

ID Sequence Length GC content
NM_020120.4 NCBI
AGCUGGGCAAUUGCUUUGCGAGGCUGGGUGUUGAGUCGAGCCGCGGGAA… 10761 nt 0.4498
Summary

UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]

Forensic Context

A study in mice demonstrated that chronic methamphetamine administration significantly dysregulates the UGGT1 in microglia, which is involved in the protein processing of endoplasmic reticulum pathway [Oladapo et al. DOI:10.3390/Ijms26020649].