Basic Information
Symbol
UGGT2
RNA class
mRNA
Alias
UDP-Glucose Glycoprotein Glucosyltransferase 2
HUGT2
UDP-Glucose:Glycoprotein Glucosyltransferase 2
UGCGL2
UDP-Glucose Ceramide Glucosyltransferase-Like 2
UDP-Glucose Ceramide Glucosyltransferase-Like 1
MGC150689
MGC117360
FLJ11485
FLJ10873
MGC87276
UGT2
UDP--Glc:Glycoprotein Glucosyltransferase 2
UDP-Glc:Glycoprotein Glucosyltransferase 2
EC 2.4.1.-
EC 2.4.1
Location (GRCh38)
13:95801580-96053482
Forensic tag(s)
Other applications
MANE select
Transcript ID
NM_020121.4
Sequence length
4850.0 nt
GC content
0.3771
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| AGCCGCGCAGCGGGAAGAGCCGGCCGAAGCGUGGCGGCCACAGACUGUG… | 4850 nt | 0.3771 |
Summary
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
Forensic Context
A study in mice demonstrated that exertional heat stroke induces a sustained epigenetic memory in the left ventricular myocardium lasting at least 30 days, characterized by widespread differential DNA methylation, including a hypomethylated promoter region of the UGGT2 gene with a 22% mean decrease across 8 CpGs [Murray et al. DOI:10.1152/physiolgenomics.00147.2021].