Basic Information

Symbol
UQCRFS1
RNA class
mRNA
Alias
Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 RISP Cytochrome B-C1 Complex Subunit 5 UQCR5 RIS1 RIP1 Cytochrome B-C1 Complex Subunit Rieske, Mitochondrial Ubiquinol-Cytochrome C Reductase Iron-Sulfur Subunit Rieske Iron-Sulfur Protein Rieske Protein UQCRFS1 Complex III Subunit 5 Epididymis Secretory Sperm Binding Protein EC 1.10.2.2 EC 7.1.1.8 MC3DN10
Location (GRCh38)
19:29205320-29213151
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Time since deposition estimation Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006003.3
Sequence length
3086.0 nt
GC content
0.4339

Transcripts

ID Sequence Length GC content
NM_006003.3 NCBI
GUGACCGGCUUGGCGGUUGGAGCGGCUGUCGCCAUGUUGUCGGUAGCAU… 3086 nt 0.4339
Summary

Predicted to enable oxidoreductase activity. Involved in mitochondrial respiratory chain complex III assembly and respiratory electron transport chain. Located in mitochondrion. Part of respiratory chain complex III. Implicated in mitochondrial complex III deficiency. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in Sarcophaga peregrina demonstrated that the UQCRFS1 shows an increasing expression tendency with intra-puparial age under both constant and fluctuating temperatures, and polynomial regression models for six differentially expressed genes, including this one, showed significant relationships (p < 0.001) between expression level and age with high coefficients of determination (R² ranging from 0.89024 to 0.98587) [Shang et al. DOI:10.3390/ani13101607].