Basic Information

Symbol
USP22
RNA class
mRNA
Alias
Ubiquitin Specific Peptidase 22 KIAA1063 USP3L Ubiquitin Carboxyl-Terminal Hydrolase 22 Ubiquitin Specific Protease 22 Deubiquitinating Enzyme 22 Ubiquitin Thioesterase 22 Ubiquitin-Specific Processing Protease 22 Ubiquitin-Specific-Processing Protease 22 Ubiquitin Specific Peptidase 3-Like Ubiquitin Thiolesterase 22 EC 3.4.19.12 EC 3.1.2.15
Location (GRCh38)
Forensic tag(s)
-

MANE select

Transcript ID
NM_015276.2
Sequence length
5189.0 nt
GC content
0.5315

Transcripts

ID Sequence Length GC content
CUUGCAGCCUCCCCUCGGCGAUCGCGCAGCCCCAUCUUUGUCCGGCCUC… 5189 nt 0.5315
Summary

Enables deubiquitinase activity; enzyme binding activity; and transcription coactivator activity. Contributes to histone H4 acetyltransferase activity. Involved in several processes, including G2/M transition of mitotic cell cycle; protein deubiquitination; and regulation of gene expression. Part of SAGA complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

No relevant information is available at the moment.