Basic Information

Symbol
USP54
RNA class
mRNA
Alias
Ubiquitin Specific Peptidase 54 BA137L10.3 BA137L10.4 C10orf29 Ubiquitin Carboxyl-Terminal Hydrolase 54 Ubiquitin Specific Protease 54 FLJ37318 Inactive Ubiquitin Carboxyl-Terminal Hydrolase 54 Inactive Ubiquitin-Specific Peptidase 54 Chromosome 10 Open Reading Frame 29 Ubiquitin Specific Proteinase 54 Ubiquitin-Specific Peptidase 54 EC 3.4.19.12
Location (GRCh38)
Forensic tag(s)
Time since deposition estimation

MANE select

Transcript ID
NM_001391956.1
Sequence length
6792.0 nt
GC content
0.4941

Transcripts

ID Sequence Length GC content
AUCACUUGCCCCACAGAUACCCUCGUGAUUAGAGGUCUUUUGCUGGAGG… 6042 nt 0.5003
AUCACUUGCCCCACAGAUACCCUCGUGAUUAGAGGUCUUUUGCUGGAGG… 3197 nt 0.4636
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6143 nt 0.4986
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6723 nt 0.4920
AGACCUGCUCUAGACGCUGACUGAAUGUUUUCCUAGUUCCAAGUCCUGC… 6768 nt 0.4911
AUCACUUGCCCCACAGAUACCCUCGUGAUUAGAGGUCUUUUGCUGGAGG… 6057 nt 0.5004
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6960 nt 0.4927
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUGCUA… 5917 nt 0.5013
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6601 nt 0.4949
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6263 nt 0.4986
Showing 1 to 10 of 21 entries
Summary

Enables K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human body fluids using a custom MPS primer panel demonstrated that the USP54 was included in a refined primer panel (V4) for time since deposition estimation [Hänggi et al. DOI:10.1016/j.fsigen.2025.103415].