Basic Information

Symbol
USP54
RNA class
mRNA
Alias
Ubiquitin Specific Peptidase 54 BA137L10.3 BA137L10.4 C10orf29 Ubiquitin Carboxyl-Terminal Hydrolase 54 Ubiquitin Specific Protease 54 FLJ37318 Inactive Ubiquitin Carboxyl-Terminal Hydrolase 54 Inactive Ubiquitin-Specific Peptidase 54 Chromosome 10 Open Reading Frame 29 Ubiquitin Specific Proteinase 54 Ubiquitin-Specific Peptidase 54 EC 3.4.19.12
Location (GRCh38)
Forensic tag(s)
Time since deposition estimation

MANE select

Transcript ID
NM_001391956.1
Sequence length
6792.0 nt
GC content
0.4941

Transcripts

ID Sequence Length GC content
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUGCUA… 5896 nt 0.4998
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUGCUA… 6037 nt 0.5012
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUGCUA… 6067 nt 0.4996
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6122 nt 0.4972
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUGCUA… 5758 nt 0.5031
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUCUCU… 6631 nt 0.4934
GACUCGGAACUGGAUAAAGGGACCAGGCUACAUUGGGAAAGAAGUGGGA… 6464 nt 0.4980
GACUCGGAACUGGAUAAAGGGACCAGGCUACAUUGGGAAAGAAGUGGGA… 6631 nt 0.4945
AUCACUUGCCCCACAGAUACCCUCGUGAUUAGAGGUCUUUUGCUGGAGG… 6621 nt 0.4942
AUCACUUGCCCCACAGAUACCCUCGUGAUUAGAGGUCUUUUGCUGGAGG… 6792 nt 0.4941
Showing 11 to 20 of 21 entries
Summary

Enables K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human body fluids using a custom MPS primer panel demonstrated that the USP54 was included in a refined primer panel (V4) for time since deposition estimation [Hänggi et al. DOI:10.1016/j.fsigen.2025.103415].