Basic Information

Symbol
USP54
RNA class
mRNA
Alias
Ubiquitin Specific Peptidase 54 BA137L10.3 BA137L10.4 C10orf29 Ubiquitin Carboxyl-Terminal Hydrolase 54 Ubiquitin Specific Protease 54 FLJ37318 Inactive Ubiquitin Carboxyl-Terminal Hydrolase 54 Inactive Ubiquitin-Specific Peptidase 54 Chromosome 10 Open Reading Frame 29 Ubiquitin Specific Proteinase 54 Ubiquitin-Specific Peptidase 54 EC 3.4.19.12
Location (GRCh38)
10:73497538-73626117
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Time since deposition estimation
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_001391956.1
Sequence length
6792.0 nt
GC content
0.4941

Transcripts

ID Sequence Length GC content
NM_152586.4 NCBI
GUAGCUAUAGCAGCCGCGGCGGUUAAGUAUGCGGCGCCAGGAGCUGCUA… 6208 nt 0.5010
Showing 21 to 21 of 21 entries
Summary

Enables K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human body fluids using a custom MPS primer panel demonstrated that the USP54 was included in a refined primer panel (V4) for time since deposition estimation [Hänggi et al. DOI:10.1016/j.fsigen.2025.103415].