Basic Information

Symbol
VGLL3
RNA class
mRNA
Alias
Vestigial Like Family Member 3 VGL-3 Transcription Cofactor Vestigial-Like Protein 3 Colon Carcinoma Related Protein Vestigial-Like Family Member 3 Vestigial Like 3 (Drosophila) Vgl-3 VGL3
Location (GRCh38)
3:86876388-86991149
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016206.4
Sequence length
10438.0 nt
GC content
0.3744

Transcripts

ID Sequence Length GC content
NM_001320493.2 NCBI
GUAUAUGCAAACCGGAGCUGGGCUCCCCACGGCUGCCCGACCCGGGCCU… 2505 nt 0.5110
NM_001320494.2 NCBI
GUAUAUGCAAACCGGAGCUGGGCUCCCCACGGCUGCCCGACCCGGGCCU… 10279 nt 0.3723
NM_016206.4 NCBI
GUAUAUGCAAACCGGAGCUGGGCUCCCCACGGCUGCCCGACCCGGGCCU… 10438 nt 0.3744
Summary

Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the VGLL3 was downregulated during short-term weight loss in subcutaneous adipose tissue, and its expression showed a significant correlation with DNA methylation at specific CpG sites, a finding that was replicated in a validation cohort of BMI-discordant monozygotic twin pairs [Bollepalli et al. DOI:10.1038/ijo.2017.245].