Basic Information
MANE select
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| AGGGUAGAGUGAGAAGCACCAGCAGGCAGUAACAGCCAACCCUUAGCCA… | 1580 nt | 0.3703 | |
| AGGGUAGAGUGAGAAGCACCAGCAGGCAGUAACAGCCAACCCUUAGCCA… | 1577 nt | 0.3697 |
Summary
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]
Forensic Context
A single-nucleus transcriptomics study of human postmortem nucleus accumbens tissue identified 17 distinct cell types, where the VIP served as a specific marker gene for the INT.VIP subcluster of spiny GABAergic interneurons [Van Den Oord et al. DOI:10.1111/Adb.13250].