Basic Information

Symbol
VPS35L
RNA class
mRNA
Alias
VPS35 Endosomal Protein Sorting Factor Like C16orf62 VPS35 Endosomal Protein-Sorting Factor-Like MGC16824 Esophageal Cancer Associated Protein Esophageal Cancer-Associated Protein Chromosome 16 Open Reading Frame 62 UPF0505 Protein C16orf62 RTSC3 EC97
Location (GRCh38)
16:19555240-19706793
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020314.7
Sequence length
3606.0 nt
GC content
0.4737

Transcripts

ID Sequence Length GC content
NM_001300743.3 NCBI
AGAACAAGCGGUCAUGUGACUGGGAAGAUGGCCGUCUUUCCUUGGCACU… 3327 nt 0.4716
NM_001365293.2 NCBI
AGAACAAGCGGUCAUGUGACUGGGAAGAUGGCCGUCUUUCCUUGGCACU… 3528 nt 0.4745
NM_001365294.2 NCBI
AGAACAAGCGGUCAUGUGACUGGGAAGAUGGCCGUCUUUCCUUGGCACU… 3405 nt 0.4708
NM_001365295.2 NCBI
AGAACAAGCGGUCAUGUGACUGGGAAGAUGGCCGUCUUUCCUUGGCACU… 3677 nt 0.4746
NM_020314.7 NCBI
AGAACAAGCGGUCAUGUGACUGGGAAGAUGGCCGUCUUUCCUUGGCACU… 3606 nt 0.4737
Summary

Involved in Golgi to plasma membrane transport and endocytic recycling. Located in endosome. Implicated in Ritscher-Schinzel syndrome. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that the VPS35L transcript, a Golgi-to-cytoplasm transport protein, increased in abundance at 1 hour postmortem [Pozhitkov et al. DOI:10.1098/rsob.160267].