Basic Information

Symbol
WDFY4
RNA class
mRNA
Alias
WDFY Family Member 4 KIAA1607 C10orf64 WD Repeat- And FYVE Domain-Containing Protein 4 Em:AC060234.3 FLJ45748 Chromosome 10 Open Reading Frame 64 EC 3.6.3.12 EC 3.5.1.18
Location (GRCh38)
10:48684873-48982959
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001394531.1
Sequence length
10082.0 nt
GC content
0.5539

Transcripts

ID Sequence Length GC content
NM_001370154.1 NCBI
AGAGUGAAACGGCGCUGAGGACUGACGAUGUGGGGCCGGGUCCUCUUCC… 2196 nt 0.5501
NM_001394531.1 NCBI
AGAGUGAAACGGCGCUGAGGACUGACGAUGUGGGGCCGGGUCCUCUUCC… 10082 nt 0.5539
NM_020945.2 NCBI
AGGGCCAUUUCCAACGGGCCUCAGAGGGAGCUGGUCUAUCCCGGCCCUG… 10023 nt 0.5527
Summary

Predicted to be involved in antigen processing and presentation. Predicted to act upstream of or within with a positive effect on CD8-positive, alpha-beta T cell activation. Predicted to act upstream of or within cellular response to virus. Predicted to be located in early endosome and endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human skin wound healing identified WDFY4 as a marker for conventional dendritic cell type 1 (cDC1) populations within the immune cell landscape of acute and chronic wounds [Liu et al. DOI:10.1016/j.stem.2024.11.013].