Basic Information

Symbol
WDR53
RNA class
mRNA
Alias
WD Repeat Domain 53 WD Repeat-Containing Protein 53 MGC64882 MGC12928 WD Domain, G-Beta Repeat-Containing Protein
Location (GRCh38)
3:196552228-196569263
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_182627.3
Sequence length
1594.0 nt
GC content
0.4624

Transcripts

ID Sequence Length GC content
NM_001345906.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGGUAUGAGGCUGGC… 2034 nt 0.4813
NM_001345907.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGAGUCUCCGGGACC… 1163 nt 0.4574
NM_001345908.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGUGCCAGCGCCACA… 1581 nt 0.4643
NM_001345909.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGGUAUGAGGCUGGC… 1661 nt 0.4672
NM_001345910.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGGUAUGAGGCUGGC… 1674 nt 0.4654
NM_001345911.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGUGCCAGCGCCACA… 784 nt 0.4426
NM_001345912.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGUGCCAGCGCCACA… 1085 nt 0.4525
NM_001345913.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGGUAUGAGGCUGGC… 1538 nt 0.4785
NM_001345914.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGUGCCAGCGCCACA… 1098 nt 0.4499
NM_001345915.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGGUGAUGCUGUGGA… 667 nt 0.4333
Showing 1 to 10 of 13 entries
Summary

This gene encodes a protein containing WD domains. The function of this gene is unknown. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human postmortem prefrontal cortex identified gene modules associated with schizophrenia symptoms, where the WDR53 was included in the blue gene module, which is located in the 3q29 deletion region and overlaps with the Multiple Sclerosis signaling pathway [Miyahara et al. DOI:10.1038/S41398-023-02449-8].