Basic Information

Symbol
WDR53
RNA class
mRNA
Alias
WD Repeat Domain 53 WD Repeat-Containing Protein 53 MGC64882 MGC12928 WD Domain, G-Beta Repeat-Containing Protein
Location (GRCh38)
3:196552228-196569263
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_182627.3
Sequence length
1594.0 nt
GC content
0.4624

Transcripts

ID Sequence Length GC content
NM_001345917.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGUGCCAGCGCCACA… 2096 nt 0.4418
NM_001345918.2 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGGUAUGAGGCUGGC… 2176 nt 0.4449
NM_182627.3 NCBI
AUCACUAGGCGCCGAGGAGGGGAGCGGGAAGCGCAGUGCCAGCGCCACA… 1594 nt 0.4624
Showing 11 to 13 of 13 entries
Summary

This gene encodes a protein containing WD domains. The function of this gene is unknown. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human postmortem prefrontal cortex identified gene modules associated with schizophrenia symptoms, where the WDR53 was included in the blue gene module, which is located in the 3q29 deletion region and overlaps with the Multiple Sclerosis signaling pathway [Miyahara et al. DOI:10.1038/S41398-023-02449-8].