Basic Information

Symbol
WEE1
RNA class
mRNA
Alias
WEE1 G2 Checkpoint Kinase WEE1A Wee1-Like Protein Kinase Wee1A Kinase EC 2.7.10.2 WEE1hu Wee1+ (S. Pombe) Homolog WEE1 Homolog (S. Pombe) Protein Kinase WEE1+ Homolog WEE1 Homolog
Location (GRCh38)
11:9573668-9593457
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003390.4
Sequence length
3588.0 nt
GC content
0.4671

Transcripts

ID Sequence Length GC content
NM_001143976.2 NCBI
AUGUAACUGAACAAUGGGCCUCGUCUGGAACUUCAUCUUACAAAGGGGC… 3437 nt 0.4082
NM_003390.4 NCBI
GGAGCCCGAACCUGAGACUGGACCUGAGGAGACCUCAGCCUCGGUGCUC… 3588 nt 0.4671
Summary

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008] CIViC Summary for WEE1 Gene

Forensic Context

No relevant information is available at the moment.