Basic Information

Symbol
WFDC5
RNA class
mRNA
Alias
WAP Four-Disulfide Core Domain 5 WAP1 DJ211D12.5 WAP Four-Disulfide Core Domain Protein 5 Putative Protease Inhibitor WAP1 P53-Responsive Gene 5 Protein PRG5 Protease Inhibitor WAP1
Location (GRCh38)
20:45109452-45115174
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_145652.4
Sequence length
1009.0 nt
GC content
0.5491

Transcripts

ID Sequence Length GC content
NM_001395506.1 NCBI
AAGGAGGUGCCAGCAUUCCAAAAGCAACAUCAGAUCAUAGAAGACAGAG… 1314 nt 0.5342
NM_145652.4 NCBI
CUCUUUCCUCUCCUGACUAAGUUUCUCUGGCUUCCCUGAGGCUGCAGGU… 1009 nt 0.5491
Summary

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.