Basic Information

Symbol
WNT2B
RNA class
mRNA
Alias
Wnt Family Member 2B WNT13 Wingless-Type MMTV Integration Site Family, Member 13 Wingless-Type MMTV Integration Site Family, Member 2B XWNT2, Xenopus, Homolog Of Protein Wnt-2b XWNT2 Protein Wnt-13
Location (GRCh38)
1:112466541-112530165
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_024494.3
Sequence length
11130.0 nt
GC content
0.4588

Transcripts

ID Sequence Length GC content
NM_001291880.1 NCBI
AACAGAGAACAGAAACCACCUCACAGCAUUGUUGUGAGCCUUAAAUGAG… 2854 nt 0.4783
NM_004185.4 NCBI
AACAGAGAACAGAAACCACCUCACAGCAUUGUUGUGAGCCUUAAAUGAG… 2925 nt 0.4786
NM_024494.3 NCBI
GCACACUAGGCCCGCAGCUCCCUUCAGCGCCGCAGACCCCCUGACACCG… 11130 nt 0.4588
Summary

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Forensic Context

A study in human ex vivo skin explants identified WNT2B as an early burn response gene, but no differential expression was observed for this mRNA within the first 24 hours post-burn in the investigated tissue [Foessl et al. DOI:10.3390/ijms22179209].