Basic Information

Symbol
WNT8A
RNA class
mRNA
Alias
Wnt Family Member 8A WNT8D Wingless-Type MMTV Integration Site Family, Member 8A Protein Wnt-8a Protein Wnt-8d
Location (GRCh38)
5:138083990-138092365
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001300939.2
Sequence length
1673.0 nt
GC content
0.5140

Transcripts

ID Sequence Length GC content
NM_001300938.2 NCBI
CUCACUUCUCUGGACUUGGCCCUGAGCUGGACCUGGUCCACUGGGGUAG… 1257 nt 0.5290
NM_001300939.2 NCBI
CUCACUUCUCUGGACUUGGCCCUGAGCUGGACCUGGUCCACUGGGGUAG… 1673 nt 0.5140
NM_058244.4 NCBI
CUCACUUCUCUGGACUUGGCCCUGAGCUGGACCUGGUCCACUGGGGUAG… 1581 nt 0.5142
Summary

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]

Forensic Context

A study in humans and mice demonstrated that the WNT8A is a component of a migrasome-related gene signature for diagnosing acute myocardial infarction, developed via machine learning from peripheral blood cohorts [Zhu et al. DOI:10.3390/biomedicines12071626].