Basic Information

Symbol
YBEY
RNA class
mRNA
Alias
YbeY Metalloendoribonuclease C21orf57 YbeY Metallopeptidase (Putative) Endoribonuclease YbeY Chromosome 21 Open Reading Frame 57 Putative Metalloprotease C21orf57 RRNA Maturation Factor Homolog Putative Ribonuclease EC 3.1.-.-
Location (GRCh38)
21:46286336-46297811
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001314025.2
Sequence length
739.0 nt
GC content
0.5291

Transcripts

ID Sequence Length GC content
NM_001006114.3 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 1513 nt 0.4924
NM_001314022.2 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 932 nt 0.6019
NM_001314023.2 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 604 nt 0.5613
NM_001314024.2 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 475 nt 0.6042
NM_001314025.2 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 739 nt 0.5291
NM_001314026.2 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 1835 nt 0.5270
NM_058181.3 NCBI
AACCCGCUCUGUGGCGGGGCUUCCGGUCGGGAGGGUCCGCCCGCUCUCG… 1061 nt 0.5778
Summary

This gene encodes a highly conserved metalloprotein. A similar protein in bacteria acts as an endoribonuclease, and is thought to function in ribosomal RNA maturation and ribosome assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Forensic Context

A study in humans demonstrated that the YBEY was identified as one of 16 overlapping transcripts in a blood transcriptome-based prediction model for post-trauma multiple organ failure, though its specific link to the syndrome is currently unknown [Duran et al. DOI:10.1186/s13613-024-01364-5].