Basic Information

Symbol
YJEFN3
RNA class
mRNA
Alias
YjeF N-Terminal Domain Containing 3 HYjeF_N3-19p13.11 YjeF N-Terminal Domain-Containing Protein 3 ApoA-I-Binding Protein 2 FLJ44968 HYjeF_N3 YjeF_N3 Apolipoprotein A1 Binding Protein AIBP2
Location (GRCh38)
19:19528861-19537584
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_198537.4
Sequence length
979.0 nt
GC content
0.6742

Transcripts

ID Sequence Length GC content
NM_001190328.2 NCBI
GGCGCCCGGGCUCACCUCGGCCAUGAGCAGCGCAGCCGGCCCAGACCCG… 829 nt 0.6888
NM_198537.4 NCBI
GGCGCCCGGGCUCACCUCGGCCAUGAGCAGCGCAGCCGGCCCAGACCCG… 979 nt 0.6742
Summary

Predicted to enable NAD(P)HX epimerase activity. Predicted to be involved in several processes, including hematopoietic stem cell proliferation; membrane raft distribution; and negative regulation of angiogenesis. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans identified a molecular signature of chronic cocaine abuse in postmortem midbrain dopamine neurons, where the YJEFN3 transcript was downregulated -1.5-fold in cocaine abusers compared to controls and was diagnostic for cohort assignment [Bannon et al. DOI:10.1038/Npp.2014.70].