Basic Information

Symbol
YKT6
RNA class
mRNA
Alias
YKT6 Vesicular SNARE Protein YKT6 V-SNARE Homolog Synaptobrevin Homolog YKT6 R-SNARE YKT6 V-SNARE Homolog (S. Cerevisiae) YKT6, S. Cerevisiae, Homolog Of YKT6 V-SNARE Protein SNARE Protein Ykt6 EC 2.3.1.- EC 2.3.1
Location (GRCh38)
7:44200959-44214294
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006555.4
Sequence length
2767.0 nt
GC content
0.5544

Transcripts

ID Sequence Length GC content
NM_001363678.2 NCBI
GGAUUGCGAGCCAGGAGGAGGAAGCCGGCGGUGGCCCCGUCAGCAGCCG… 2665 nt 0.5576
NM_001410874.1 NCBI
GGAUUGCGAGCCAGGAGGAGGAAGCCGGCGGUGGCCCCGUCAGCAGCCG… 2818 nt 0.5522
NM_006555.4 NCBI
GGAUUGCGAGCCAGGAGGAGGAAGCCGGCGGUGGCCCCGUCAGCAGCCG… 2767 nt 0.5544
Summary

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]

Forensic Context

A study in humans demonstrated that the YKT6 gene was downregulated in subcutaneous adipose tissue during short-term weight loss in obese participants [Bollepalli et al. DOI:10.1038/ijo.2017.245].