YTH N6-Methyladenosine RNA Binding Protein F1
C20orf21
Dermatomyositis Associated With Cancer Putative Autoantigen 1
YTH N(6)-Methyladenosine RNA Binding Protein 1
YTH N6-Methyladenosine RNA Binding Protein 1
YTH Domain-Containing Family Protein 1
YTH Domain Family, Member 1
YTH Domain Family 1
FLJ20391
DACA-1
DF1
YTH Domain Family Protein 1
Enables N6-methyladenosine-containing RNA reader activity and ribosome binding activity. Involved in mRNA destabilization; positive regulation of translational initiation; and stress granule assembly. Located in P-body and cytoplasmic stress granule. Implicated in colorectal cancer. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice and human tissues demonstrated that the YTHDF1 binds to m6A-modified COL3A1, COL1A1, and ELN mRNAs to stabilize them, promoting pathological extracellular matrix deposition in hypertrophic scarring [Zhang et al. DOI:10.7150/ijbs.114988].