Basic Information

Symbol
ZBTB43
RNA class
mRNA
Alias
Zinc Finger And BTB Domain Containing 43 ZBTB22B Zinc Finger Protein 297B KIAA0414 ZNF297B ZNF-X Zinc Finger And BTB Domain-Containing Protein 22B Zinc Finger And BTB Domain-Containing Protein 43 FLJ22470 ZnF-X
Location (GRCh38)
9:126804988-126838210
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_014007.4
Sequence length
5940.0 nt
GC content
0.4364

Transcripts

ID Sequence Length GC content
NM_001135776.2 NCBI
GAAUCUGUUGCGGCAGCUGAGGCUACAACAGGCCUGCGCCGGCGGCAGA… 5817 nt 0.4379
NM_014007.4 NCBI
GAAUCUGUUGCGGCAGCUGAGGCUACAACAGGCCUGCGCCGGCGGCAGA… 5940 nt 0.4364
Summary

Enables RNA polymerase III general transcription initiation factor binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans undergoing cardiac surgery with cardiopulmonary bypass demonstrated that acute left ventricular ischemia induces differential expression of 21 microRNAs, including upregulated miR-339-5p and downregulated miR-139-5p, in myocardial tissue [Saddic et al. DOI:10.1152/physiolgenomics.00049.2015].