Basic Information

Symbol
ZCCHC12
RNA class
mRNA
Alias
Zinc Finger CCHC-Type Containing 12 SIZN1 PNMA7A SIZN Zinc Finger CCHC Domain-Containing Protein 12 Paraneoplastic Ma Antigen Family Member 7A Smad-Interacting Zinc Finger Protein 1 FLJ16123 Zinc Finger, CCHC Domain Containing 12
Location (GRCh38)
X:118823824-118826968
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_173798.4
Sequence length
2197.0 nt
GC content
0.5075

Transcripts

ID Sequence Length GC content
NM_001312891.2 NCBI
GGCGCUGCCUCGUCUCUGCUACCCCUGGUUGGGCGGCCCUGCGAAGCAG… 2145 nt 0.5077
NM_173798.4 NCBI
GGCGCUGCCUCGUCUCUGCUACCCCUGGUUGGGCGGCCCUGCGAAGCAG… 2197 nt 0.5075
Summary

This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Forensic Context

The review of proteomic applications in forensic science identifies the ZCCHC12 as a protein marker showing loss post-mortem in bone, contributing to the estimation of the late post-mortem interval [Alex et al. DOI:10.1016/j.scijus.2025.101320].