Basic Information

Symbol
ZDHHC1
RNA class
mRNA
Alias
ZDHHC Palmitoyltransferase 1 ZNF377 Zinc Finger DHHC-Type Containing 1 HSU90653 C16orf1 DHHC Domain-Containing Cysteine-Rich Protein 1 Zinc Finger DHHC Domain-Containing Protein 1 Palmitoyltransferase ZDHHC1 Zinc Finger Protein 377 DHHC-1 Zinc Finger, DHHC Domain Containing 1 Probable Palmitoyltransferase ZDHHC1 Chromosome 16 Open Reading Frame 1 EC 2.3.1.225
Location (GRCh38)
16:67394152-67416833
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_001323627.2
Sequence length
2252.0 nt
GC content
0.6510

Transcripts

ID Sequence Length GC content
NM_001323627.2 NCBI
AGCGCCGGACGAGGCCCAGCCAGUCUGGGUCUGGCCUGGCCGCCCCUCC… 2252 nt 0.6510
NM_013304.3 NCBI
AGCGCCGGACGAGGCCCAGCCAGUCUGGGUCUGGCCUGGCCGCCCCUCC… 2317 nt 0.6504
Summary

Enables protein-cysteine S-palmitoyltransferase activity. Involved in antiviral innate immune response; protein palmitoylation; and regulation of defense response. Located in Golgi apparatus and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans evaluating placental mRNA markers for forensic pregnancy diagnostics found that the ZDHHC1 did not demonstrate a pregnancy-specific expression pattern in whole blood analysis [Gauvin et al. DOI:10.1007/S00414-008-0315-6].