Basic Information

Symbol
ZFAND2A
RNA class
mRNA
Alias
Zinc Finger AN1-Type Containing 2A AIRAP Arsenite Inducible RNA Associated Protein Zinc Finger, AN1-Type Domain 2A AN1-Type Zinc Finger Protein 2A
Location (GRCh38)
7:1151903-1160771
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_182491.4
Sequence length
878.0 nt
GC content
0.5194

Transcripts

ID Sequence Length GC content
NM_001365381.2 NCBI
AAGGCCCAGACGGCUCUCAGAUCCGGGGGCUGCGGAUAAAUCCCCGUAG… 785 nt 0.5274
NM_001365383.1 NCBI
AAGGCCCAGACGGCUCUCAGAUCCGGGGGCUGCGGAUAAAUCCCCGUAG… 4207 nt 0.5132
NM_182491.4 NCBI
AAGGCCCAGACGGCUCUCAGAUCCGGGGGCUGCGGAUAAAUCCCCGUAG… 878 nt 0.5194
Summary

Predicted to enable zinc ion binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein targeting to ER. Predicted to act upstream of or within cellular response to arsenic-containing substance and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome complex. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the ZFAND2A was identified as one of 16 overlapping blood transcriptomic biomarkers for early prediction of multiple organ failure following blunt trauma, with the biomarker panel achieving high predictive accuracy (e.g., AUROC up to 0.907 in test sets) [Duran et al. DOI:10.1186/s13613-024-01364-5].