Predicted to enable carbohydrate binding activity and peptidoglycan binding activity. Predicted to be involved in protein transport. Predicted to act upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in Golgi lumen and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2025]
Forensic Context
A study in humans developed a multiplex RT-PCR assay for rectal mucosa identification, where the ZG16 was selected as a candidate marker based on characteristic expression in the rectum and was positive in 16 of 19 rectal mucosa samples, with no detection in other tested body fluids when applying a cutoff value, and it showed a positive correlation with PHGR1 [Akutsu et al. DOI:10.1016/J.Fsigen.2022.102712]. Another human study evaluating mRNA-based methods noted the ZG16 is mentioned in the literature as a useful marker for rectal mucosa, though it was not experimentally studied in that work [Martin et al. DOI:10.1016/j.fsigen.2025.103297].