Basic Information

Symbol
ZGPAT
RNA class
mRNA
Alias
Zinc Finger CCCH-Type And G-Patch Domain Containing KIAA1847 ZC3HDC9 GPATCH6 GPATC6 ZC3H9 ZIP Zinc Finger CCCH-Type With G Patch Domain-Containing Protein Zinc Finger And G Patch Domain-Containing Protein Zinc Finger CCCH Domain-Containing Protein 9 G Patch Domain-Containing Protein 6 DJ583P15.3 MGC44880 FLJ14972 Zinc Finger, CCCH-Type With G Patch Domain Zinc Finger CCCH-Type With G-Patch Domain
Location (GRCh38)
20:63707353-63736150
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_181485.3
Sequence length
1867.0 nt
GC content
0.6411

Transcripts

ID Sequence Length GC content
NM_001083113.2 NCBI
GGGGAACACACUCGCUGCAGCCCCGCCUGGGCCACGGCACCCUCGAGCG… 1905 nt 0.6472
NM_001195653.2 NCBI
ACUUCCGGAAGCGGCGGCGCUCGGGAGGAAGUGCCGAUCGGCUGCUGGG… 1918 nt 0.6439
NM_001195654.2 NCBI
ACUUCCGGAAGCGGCGGCGCUCGGGAGGAAGUGCCGAUCGGCUGCUGGG… 1910 nt 0.6466
NM_032527.5 NCBI
ACUUCCGGAAGCGGCGGCGCUCGGGAGGAAGUGCCGAUCGGCUGCUGGG… 1997 nt 0.6460
NM_181485.3 NCBI
ACUUCCGGAAGCGGCGGCGCUCGGGAGGAAGUGCCGAUCGGCUGCUGGG… 1867 nt 0.6411
Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A review of RNA-Seq studies in post-mortem human brains notes that the ZGPAT was identified as a differentially expressed gene in the hippocampus, representing a shared neuronal function-associated molecular change in addiction when comparing cocaine-addicted and alcoholic brains to controls [Wu et al. DOI:10.1111/Pcn.12550].