Basic Information

Symbol
ZNF146
RNA class
mRNA
Alias
Zinc Finger Protein 146 OZF Only Zinc Finger Protein Zinc Finger Protein OZF
Location (GRCh38)
19:36214602-36238774
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007145.3
Sequence length
3347.0 nt
GC content
0.3887

Transcripts

ID Sequence Length GC content
NM_001099638.2 NCBI
GAGUGCGCAAGCGCAGCGCACCGAGUGGACAUUUUGGUCUUUGUCCGCG… 3273 nt 0.3859
NM_001099639.2 NCBI
GAGUGCGCAAGCGCAGCGCACCGAGUGGACAUUUUGGUCUUUGUCCGCG… 3232 nt 0.3824
NM_007145.3 NCBI
GAGUGCGCAAGCGCAGCGCACCGAGUGGACAUUUUGGUCUUUGUCCGCG… 3347 nt 0.3887
Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human keratinocytes demonstrated that the ZNF146 was downregulated (0.65-fold) following 5 Gy X-ray irradiation [Koike et al. DOI:10.1269/jrr.46.173]. A separate study in human burn patients analyzing blood samples found that the ZNF146 exhibited a significantly decreasing expression trend from 0 to 7 days after severe burn injury [Wu et al. DOI:10.1016/j.burns.2018.08.022].