Basic Information

Symbol
ZNF18
RNA class
mRNA
Alias
Zinc Finger Protein 18 ZKSCAN6 ZNF535 KOX11 HDSG1 ZSCAN38 Zfp535 Zinc Finger Protein With KRAB And SCAN Domains 6 Heart Development-Specific Gene 1 Protein Zinc Finger Protein 18 (KOX 11) Zinc Finger Protein 535 Zinc Finger Protein KOX11
Location (GRCh38)
17:11977439-11997475
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001303281.2
Sequence length
2295.0 nt
GC content
0.4959

Transcripts

ID Sequence Length GC content
NM_001303281.2 NCBI
ACCCAGCUCCCGGAAGUGCGCCCGGAGCCGGCGCCGCGGGCCGAGUGUC… 2295 nt 0.4959
NM_001303282.2 NCBI
ACCCAGCUCCCGGAAGUGCGCCCGGAGCCGGCGCCGCGGGCCGAGUGUC… 2292 nt 0.4956
NM_144680.4 NCBI
AUCUGCGUCCGCACCUGACUCAGCUGGGCACCCCGGAGCUACGGAGGGG… 2773 nt 0.5074
Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human leukocytes from severe burn patients identified the ZNF18 as a transcription factor with sustained increased expression post-burn, classifying it as a top biomarker for recovery and suggesting it may be a driver for inducing an immunosuppressive state [Xu et al. DOI:10.1159/000493451].