Basic Information

Symbol
ZNF350
RNA class
mRNA
Alias
Zinc Finger Protein 350 ZBRK1 Zinc Finger And BRCA1-Interacting Protein With A KRAB Domain 1 ZFQR KRAB Zinc Finger Protein ZFQR Zinc Finger Protein ZBRK1
Location (GRCh38)
Forensic tag(s)
Chronological age estimation

MANE select

Transcript ID
NM_021632.4
Sequence length
2355.0 nt
GC content
0.4263

Transcripts

ID Sequence Length GC content
ACUCCAGAAGUAGGAGCAGUUUACGGAAGUGUAACGUUGAGGCCCUUCU… 2355 nt 0.4263
Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A review of multi-omics studies in humans identified the ZNF350 as a top list gene associated with 11 epigenetic aging clocks [Solovev et al. DOI:10.1016/j.mad.2019.111192].