Basic Information

Symbol
ZNF366
RNA class
mRNA
Alias
Zinc Finger Protein 366 Dendritic Cell-Specific Transcript Protein DC-SCRIPT FLJ39796 DCSCRIPT
Location (GRCh38)
5:72439903-72507410
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_152625.3
Sequence length
6262.0 nt
GC content
0.4875

Transcripts

ID Sequence Length GC content
NM_152625.3 NCBI
CUCUUUCUUAAGUCAUUCGAAACACUGUCCCUGCGAGUUCUUUAAGUUC… 6262 nt 0.4875
Summary

Enables nuclear estrogen receptor binding activity and transcription corepressor activity. Involved in negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription by RNA polymerase II; and response to estrogen. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human patients identified the ZNF366 as one of ten hub genes for predicting heart failure progression post-myocardial infarction via machine learning algorithms [Xu et al. DOI:10.3389/fgene.2025.1592985].