Basic Information

Symbol
ZNF76
RNA class
mRNA
Alias
Zinc Finger Protein 76 ZNF523 D6S229E Zfp523 Zinc Finger Protein 76 (Expressed In Testis) Zinc Finger Protein 523
Location (GRCh38)
6:35258909-35295985
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003427.5
Sequence length
2653.0 nt
GC content
0.5873

Transcripts

ID Sequence Length GC content
NM_001292032.2 NCBI
GCGCGCGGGCGGGCGGGCUAUGGCGCAGGCGGGUUGUGGGGCCGGCGCU… 2488 nt 0.5832
NM_003427.5 NCBI
GCGCGCGGGCGGGCGGGCUAUGGCGCAGGCGGGUUGUGGGGCCGGCGCU… 2653 nt 0.5873
Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human leukocytes from severe burn patients identified the ZNF76 as a top sustained increasing gene (SIG) with expression rising from the healthy state through the late recovery phase, classifying it as a biomarker for burn recovery and noting its role as a transcription factor whose up-regulation may be a driver for inducing an immunosuppressive state post-burn [Xu et al. DOI:10.1159/000493451].