Basic Information

Symbol
ZNHIT3
RNA class
mRNA
Alias
Zinc Finger HIT-Type Containing 3 Thyroid Hormone Receptor Interactor 3 TRIP3 Hit1 Zinc Finger HIT Domain-Containing Protein 3 TR-Interacting Protein 3 Zinc Finger, HIT Type 3 HNF-4a Coactivator TRIP-3 Thyroid Receptor Interacting Protein 3 Thyroid Receptor-Interacting Protein 3 Zinc Finger, HIT Domain Containing 3 PEHO
Location (GRCh38)
17:36486629-36499310
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004773.4
Sequence length
905.0 nt
GC content
0.4276

Transcripts

ID Sequence Length GC content
NM_001281432.2 NCBI
AGUCUCCUUCCACAAAACCAUGGCGUCGCUCAAAUGUAGCACCGUCGUC… 2012 nt 0.4861
NM_001281433.2 NCBI
AGUCUCCUUCCACAAAACCAUGGCGUCGCUCAAAUGUAGCACCGUCGUC… 871 nt 0.4317
NM_001281434.2 NCBI
AGUCUCCUUCCACAAAACCAUGGCGUCGCUCAAAUGUAGCACCGUCGUC… 737 nt 0.4410
NM_004773.4 NCBI
AGUCUCCUUCCACAAAACCAUGGCGUCGCUCAAAUGUAGCACCGUCGUC… 905 nt 0.4276
Summary

Predicted to enable nuclear thyroid hormone receptor binding activity. Predicted to be involved in box C/D snoRNP assembly; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and snoRNA localization. Located in cytoplasm and nucleus. Implicated in PEHO syndrome. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that a 7-day overfeeding intervention in lean and obese men induced differential expression of 45 genes in abdominal subcutaneous adipose tissue, with six genes showing a significant interaction between adiposity status and treatment [Shea et al. DOI:10.3945/ajcn.2008.25970].