Basic Information

Symbol
ZPBP
RNA class
mRNA
Alias
Zona Pellucida Binding Protein ZPBP1 Zona Pellucida-Binding Protein 1 Inner Acrosomal Membrane IAM38 SP38 SPGF66 Sp38
Location (GRCh38)
7:49850421-50121329
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007009.3
Sequence length
1195.0 nt
GC content
0.4209

Transcripts

ID Sequence Length GC content
NM_001159878.2 NCBI
GUUGCCUAACGACCUUCCGCGCGGACGGUGGGCAGGCGACGGCGGCGUG… 1192 nt 0.4211
NM_007009.3 NCBI
GUUGCCUAACGACCUUCCGCGCGGACGGUGGGCAGGCGACGGCGGCGUG… 1195 nt 0.4209
Summary

ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008]

Forensic Context

A collaborative study in humans demonstrated that the ZPBP was evaluated in a preliminary study but gave inconsistent results during singleplex testing and was therefore not included in the validated semen pentaplex used for forensic mRNA profiling [Haas et al. DOI:10.1016/j.fsigen.2012.10.011].