Caspase Recruitment Domain Family Member 11
CARMA1
BIMP3
Caspase Recruitment Domain-Containing Protein 11
Bcl10-Interacting Maguk Protein 3
CARD-Containing MAGUK Protein 1
Carma 1
Caspase Recruitment Domain Family, Member 11
Card-Maguk Protein 1
IMD11A
BENTA
IMD11
PPBL
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008] CIViC Summary for CARD11 Gene
Forensic Context
No relevant information is available at the moment.