Actin Related Protein 1A
ARP1
Arp1A
ARP1 Actin-Related Protein 1 Homolog A, Centractin Alpha
ARP1 Actin Related Protein 1 Homolog A
Centrosome-Associated Actin Homolog
Alpha-Centractin
Centractin
Actin-RPV
CTRN1
ARP1 (Actin-Related Protein 1, Yeast) Homolog A (Centractin Alpha)
Epididymis Secretory Sperm Binding Protein
Centractin Alpha
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]
Forensic Context
No relevant information is available at the moment.