Basic Information

Symbol
CD52
RNA class
mRNA
Alias
CD52 Molecule HE5 EDDM5 CDW52 Human Epididymis-Specific Protein 5 CD52 Antigen (CAMPATH-1 Antigen) Epididymal Secretory Protein E5 Cambridge Pathology 1 Antigen CAMPATH-1 Antigen Epididymis Secretory Sperm Binding Protein Li 171mP CDW52 Antigen (CAMPATH-1 Antigen) CD52 Antigen HEL-S-171mP CDw52 He5
Location (GRCh38)
1:26317958-26320523
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001803.3
Sequence length
467.0 nt
GC content
0.5225

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-141.30 kcal/mol
Thermodynamic ensemble
Free energy: -148.42 kcal/mol
Frequency: 0.0000
Diversity: 92.88
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.....(((((((((((.........((((((....)).))))...(((((.......................))))).........(((((.((((....))))))))).(((.......))))).)))))))..............((.......)).(((((.((((.(((.((.......)))))((((((..((..........))..))))))......((((((..(((...)))..))))))..(((((...((((...((((((((((((.......((((((.......(((....)))...(((((((.......))))))).(((((.....))))).(((.((....)).)))...)))))).....)))))))..........)))))))))...)))))..((((........)))).))))))))).....((((.((....)))))))).
Thermodynamic Ensemble Prediction
.....{,(((((((({.........((((((....)).))))...(((({............{,{|.,.,,,.,}}}}.........(((((.((((....))))))))).{{{.......}))}}.)))))))...........,,,({.......{{.((((({,{{{.{((.((.......)))))({|{{{..{{........,,)),.}}})))......((((((..(((...)))..))))))..(((((...((((...((((((((((((,,.....((((((.......(((....)))...(((((((.......))))))).(((((.....))))).(((.((....)).)))...))))))..,,.))))))}.,,,......}))))))))...))))),}||||...}}.},}},,.)))))||||,....,,||,||,,.,))}}}}},.

Transcripts

ID Sequence Length GC content
NM_001803.3 NCBI
AGACAGCCCUGAGAUCACCUAAAAAGCUGCUACCAAGACAGCCACGAAG… 467 nt 0.5225
Summary

Involved in positive regulation of cytosolic calcium ion concentration. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in sperm midpiece. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the CD52 mRNA, used as a blood-specific marker in a coding region SNP (cSNP) sequencing assay, exhibited cross-reactivity in semen samples [Liu et al. DOI:10.1016/j.fsigen.2024.103066].