Basic Information

Symbol
ACYP1
RNA class
mRNA
Alias
Acylphosphatase 1 Acylphosphatase 1, Erythrocyte (Common) Type Acylphosphatase, Organ-Common Type Isozyme Acylphosphatase, Erythrocyte Isozyme Acylphosphate Phosphohydrolase 1 Acylphosphatase-1 ACYPE EC 3.6.1.7
Location (GRCh38)
14:75053221-75069483
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Mixture deconvolution
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001107.5
Sequence length
580.0 nt
GC content
0.4121

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-154.00 kcal/mol
Thermodynamic ensemble
Free energy: -165.12 kcal/mol
Frequency: 0.0000
Diversity: 111.72
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((((.((......(((.((.(((((((((.((..((((.((.....)).))))..))......((((((((.(((......(((((((((((..((((........................))))...)))))))..)))).....))).))))))))............))))))))).)).))).((((.((....))))))(((((....(((((......)))))..))))).)).)))))))))))((((((((((...((((....((((..(((((((...((((.((..............(((((((..((((.....)))).))))))))))))).....)))))))...))))........))))........(((((........)))))(((((((((.(((((((((...))))))))).))))))))).((((((....)))))).......(((..(((..(((((((((....))).))))))..)))..)))))))))).)))(((((..(((....)))......((((((..........)))))).)))))
Thermodynamic Ensemble Prediction
(((((((((((.((...,,{(({,({.((({(((((..(,{((((,((..{{.,|.}},,..}}......((((((((.(({,{....(((((((((((..{{((,.,.{{,......,,,,}},,...}})}...)))))))}.})))....}))).))))))))....,......,))))))))).)}.})))||{|||{.,,.)))))}(((((....(((((......)))))..))))).)).)))))))))))((((((((((...((((....((((..(((((((...,{{{.,............,.{(((((((..((((.....)))).))))))))}}}}}.....)))))))...))))........))))........{{{{{.,......}}||,(((((((((.(((((((((...))))))))).))))))))).||({({....}}}}|}....,..{{{..(({..{{{{{{({{....}))}})))))..)))..)),))))))),,))(((((..,{{....}},......((((((..........)))))).)))))

Transcripts

ID Sequence Length GC content
NM_001107.5 NCBI
GCGCGCCUUGGUGAGCCGUUGGCGUGGUGGUCCCGGAGUGAUCCUGGCA… 580 nt 0.4121
NM_001302616.2 NCBI
GCGCGCCUUGGUGAGCCGUUGGCGUGGUGGUCCCGGAGUGAUCCUGGCA… 562 nt 0.4057
NM_001302617.2 NCBI
AGUCAGUGUCCGGCCAACUCUGCAGCUCGGUCCAGCCCUGCCCUUGGGG… 790 nt 0.4848
Summary

This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Forensic Context

A study in humans demonstrated that the ACYP1 exhibited a Gini impurity score of 0, indicating it was present in some pure peripheral blood samples but was absent in all analyzed mixtures containing blood and in mixtures without blood [Shehata et al. DOI:10.1016/j.fsigen.2025.103343].