Caudal Type Homeobox 1
Caudal Type Homeo Box Transcription Factor 1
Caudal-Type Homeobox Protein 1
Homeobox Protein CDX-1
Caudal Type Homeobox Transcription Factor 1
Caudal-Type Homeobox Protein CDX1
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008]
Forensic Context
A study in humans developed a multiplex RT-PCR assay for identifying rectal mucosa as evidence of anal penetration, evaluating six candidate mRNA markers including the CDX1 [Akutsu et al. DOI:10.1016/J.Fsigen.2022.102712].