Calcineurin Like EF-Hand Protein 1
CHP
SLC9A1BP
Sid470p
P22
P24
EF-Hand Calcium-Binding Domain-Containing Protein P22
Calcineurin B Homologous Protein 1
Calcineurin Homologous Protein
Calcium-Binding Protein CHP
Calcium-Binding Protein P22
Calcineurin B-Like Protein
Calcium Binding Protein P22
SLC9A1 Binding Protein
Calcineurin B Homolog
SPAX9
This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq, Jul 2008]
Forensic Context
A study in humans demonstrated that a 7-day overfeeding intervention in lean and obese men induced differential expression of 45 genes in abdominal subcutaneous adipose tissue, with the CHP1 being up-regulated in response to the positive energy challenge [Shea et al. DOI:10.3945/ajcn.2008.25970].